Two major title fights highlight one of the most significant events in UFC history on September 14. Sean O'Malley defends the UFC bantamweight title against Merab Dvalishvili, while Alexa Grasso and Valentina Shevchenko compete in a trilogy for the UFC flyweight title. The show takes place at The Sphere in Las Vegas and will air on ESPN+ PPV in the U.S.

O'Malley and Dvalishvili are two of the best at what they do. The former is a striker, while Dvalishvili is a dominant wrestler. Known as "Suga", O'Malley is on an eight-fight unbeaten streak, while his Georgian opponent is on a ten-fight win streak. While they respect the other's crafts, O'Malley and Dvalishvili believe they have the other scouted.

"Sean was running a lot," Dvalishvili said regarding his fight against Aljamain Sterling via Bleacher Report. "[Sterling] was the one who has to chase him. "He's going to do the same thing against me. I have to be [the] one who's gonna step in and who's gonna start fighting, because he's gonna be just running and fighting from the distance."

WATCH: UFC 306: Sean O'Malley vs. Merab Dvalishvili on ESPN+

"Even if I go out there and knock Merab out very early — which I probably will do — they'll still 'but you haven't fought a wrestler that was able to take you down,'" O'Malley said. "It's always a lose-lose.

"I mean if he does take me down, and I'm able to deal with that and I get back up, knock him out, submit him, whatever it is, win a decision, maybe they stop saying all that. But my goal is to go out there and not even have to deal with that: keep distance, keep him at the end of my punches and put his lights out."

Shevchenko lost against Grasso at UFC 285 via a surprise submission from the Mexican, ending a nine-fight win streak. The rematch last year saw the fight end in a draw. Grasso looks to put Shevchenko behind her while the latter is ready to return to the top.

The Sporting News will provide results from the entire UFC 306 card!

UFC 306 full card results

Main Card

• Sean O'Malley (c) vs. Merab Dvalishvili for the UFC bantamweight title
• Alexa Grasso (c) vs. Valentina Shevchenko 3 for the UFC flyweight title
• Brian Ortega vs. Diego Lopes; Featherweight
• Daniel Zellhuber vs. Esteban Ribovics; Lightweights
• Ronaldo Rodríguez vs. Ode' Osbourne; Flyweights

Prelims

• Ignacio Bahamondes vs. Manuel Torres; Lightweights
• Irena Aldana vs. Norma Dumont; Bantamweights
• Edgar Chairez vs. Joshua Van; Flyweights
• Yazmin Jauregui vs. Ketlen Souza; Strawweights

Early Prelims

• Raul Rosas Jr. vs. Aoriqileng; Bantamweights

UFC 306 start time

• Date: Saturday, September 14
• Location: The Sphere - Las Vegas
• Time: 10 p.m. ET | 7 p.m. PT | 3 a.m BST 12 p.m. AEST

The UFC 306 main card starts at 10 p.m. ET. The prelims begin at 8 p.m. ET, while the early prelims begin at 7:30 p.m. ET. The main event should begin around 12:30 a.m. ET, depending on how long the undercard fights last.

How to watch UFC 306 prelims

• Channel: ESPN
• Live stream: Fubo

The prelims, starting at 8 p.m. ET, will air on ESPN. It will also be streamed via Fubo which has a free trial so you can try it before you buy.

How to watch UFC 306 main card

• Live stream 
  • U.S.: ESPN+ ($79.99 PPV fee plus $10.99/month membership)
  • AU: Kayo ($59.95)
  • U.K.: TNT Sports (￡3.99/month or ￡39.99/year via discovery+)

UFC 306 is available on ESPN+ and ESPN+ PPV in the U.S.

The UFC 306 main card is available via pay-per-view on ESPN+, which also requires a subscription. The PPV price for UFC 306 is $79.99 for current subscribers. New subscribers can pay a bundle price of $134.98 for the UFC 306 pay-per-view and an ESPN+ annual subscription, which offers savings of more than 30 percent.