Prisco's Week 2 NFL picks: Vikings upset 49ers, Patriots improve to 2-0, Giants take down Commanders

Pete Prisco reveals all his Week 2 picks for the 2024 season, including a few upsets

By Pete Prisco Sep 12, 2024 at 4:41 pm ET• 6 min read

As I told you last week, I hate picking Week 1 NFL games.

But, surprisingly, I had a decent week.

I went 8-6-2 against the spread and 10-6 straight up for a decent start to the 2024 NFL season. The unpredictability of the first week is the challenge. The next part is trying to figure out how much of Week 1 is real.

Let's hope I did a decent job of finding the fakes here as I look to keep my head above .500 after two weeks.

Week 1 wasn't so bad.

Let's hope Week 2 is even better. 

Buffalo Bills at Miami Dolphins (-1.5)

Thursday, 8:15 p.m. ET (Prime Video)

Josh Allen has owned the Miami Dolphins in his career with an 11-2 record. That won't change in this one. It's always tough on the Bills playing in the heat, but this is a night game. Sure, it's on a short week, but the Bills will do enough on defense and Allen will win it late. He continues his mastery over the Dolphins. 

Pick:Bills 28, Dolphins 24

Las Vegas Raiders at Baltimore Ravens (-9.5)

Sunday, 1 p.m. ET (CBS, Paramount+)

This a second straight road game for the Raiders against a team playing its home opener with rest -- and it's on the East Coast. That's a brutal trip for the Raiders. Their offense struggled against the Chargers and it will here. The Ravens won't struggle. Lamar Jackson has a nice game.